This course explores the relationships between new media languages and physical space. Using technologies ranging from the intimacy of handheld devices to the monumental scale of a building façade, in this class we will learn to activate the space through multimedia content and relational strategies. Based on conceptualizations such as "Relational Architecture" by Lozano Hemmer and the "Poetics of Augmented Space" by Lev Manovich, we will design interactive and audiovisual elements to enhance and re-contextualize spatial experiences that are media-rich, relational, and responsive. We will use software, video-projectors, VR headsets and various tracking technologies to investigate techniques of video-mapping, mixed reality, computer vision and interactive media. We will learn to deploy not only vision, but also hearing and touch to create true immersive and multi-sensorial environments. The class comprises of lectures, hands-on workshops and individual projects. The students will gain a deep understanding of topics on spatial thinking, spatial design and user-generated experiences related to space, as well as a theoretical and historical understanding of installation and interactive art.